Histological structure and evaluation of cellular layers of Large intestine in Guinea pig (Cavia porcellus)

The Aim of this study is to determine the histological structure in wall layers large intestine guinea pig. cecum and colon was characterized by a delicate lining that moisturized mucus also gel by-product bacterial fermentation. This performed on ascending descending five health animals. composed four tunicae (mucosa, submucosa, muscularis serosa, tunica mucosa consist epithelium, lamina propria mucosa. lumen lined simple columnar epithelium with prominent goblet cells. epithelial surface covered openings tubular intestinal glands which penetrate deep into thick absorptive cells absorb water salt, were secrete mucus, scattered Paneth Crypts Lie beckon (intestinal glands) are observe most mammals, extending from through thickness they open lumen. Muscularis mucosa, consisted very thin two inner circular outer longitudinal smooth muscles, greater adult type submucosa consists dense irregular connective tissue. muscular layer internal external mean their decreased toward last parts. Thus, serous coat loose tissue, decreases